What We Offer

The Chem-Master International team has the skill and experience necessary to meet the requirements of any client. Providing quick and cost effective solutions we are a skilled research, development, and manufacturing company. We specialize in contract projects both short-term and long-term, providing services such as Chemical Synthesis, Process Chemistry and Chemical Research. We offer intermediates, reference compounds, starting materials, and congens and/or derivatives of lead compounds. Compounds are made to order in scales ranging from milligrams to kilogram quantities.

Our chemists work in a well-equipped facility with ready access to literature/reaction databases and literature retrieval services.Please read on to learn more about our expertise in the areas of Chemical Synthesis, Process Chemistry, Chemical Research services. We also offer two basic types of Service Contracts but can customize service contracts to suit the clients needs.

Our Contract Options

Chem-Master International offers several types of service contracts to meet individual needs:

Fixed Bid Contract

  • A fixed quote price is provided for the project. This is payable only upon project completion.
  • Intellectual property (IP) ownership depends on the agreement.

Time and Materials (T&M) Contract

  • Here initial estimated quote for the labor and materials is provided but the client pays only for costs spent on time and materials.
  • All IP is owned by the client.

Full-Time Equivalent (FTE) Contract

  • The client may retain one or more of ChemMaster International's scientist to work on the designated projects full-time.
  • The client is invoiced periodically (on a mutually agreed schedule) for the contracted amount. This also includes the cost for materials.
  • All IP is owned by the client.
  • The advantages of this type of contract are reliable capability, flexibility and efficiency.

Joint Venture Contract

  • ChemMaster International also offers joint venture contracts where both parties share the burden of the research and development.
  • All IP is shared by both parties.

Chemical Synthesis

Custom Synthesis

The Custom Synthesis process requires the client to provide literature methods or their own synthetic route in which all details such as the reaction times, solvents, temperatures, analytical data, purification methods, yields, etc. are provided. If the client is unable to provide all of the technical information the Chem-Master chemistry team will evaluate the synthesis, determine the viability of the project than provide an estimate before the project is initiated. The cost estimate also provides a timeframe. Due to the unpredictable nature of synthetic chemistry all work is done on a best effort basis although with a success rate of over 95% we do have the skills to complete the requirements for most clients.

Contract Synthesis

Contract Synthesis process involves the client providing limited or no synthetic information. This process involves Chem-Master International working on determining the best route of synthesis. The Chem-Master International team will conduct literature research on target compounds or pertinent synthetic methods. We may conduct preliminary experiments to determine feasibility of the project and will provide an estimate of costs and time, before the project is initiated.

Our synthetic approach involves the assignment of a specified number of scientists dedicated to the project on a full-time basis. Samples of the intermediate compounds are available to the client at any stage of the project and all progress is regularly communicated to the client via meetings and written reports. Either party reserves the right to stop the project with advance notice. Upon the termination of the project, the client is provided with a report detailing the R&D conducted on the project (including literature search results, synthesis methods, purification methods, etc.). At the customer’s request we will also provide any available intermediate compounds that were prepared. The cost of the project on its completion or termination, irrespective of result, will be communicated to the client.

Process Chemistry

Chem-Master prides itself at being expert in assisting our clients to develop new and proprietary routes to existing compounds. We will also take an existing synthesis and develop a scalable process using our in-house talent and state-of-the-art technology, including statistical design of experiments, real-time reaction monitoring to generate detailed reaction/impurity profiles, and further process development. Our staff has experience in developing and transferring projects from our research laboratories to pilot plant scale.

One of our recent projects include is a multi-year collaboration with a biotechnology company in which the core requirement is the development of a commercial API manufacturing process starting from a multi-step medicinal chemistry route.

Services being offered include:

  • Process development
  • Route scouting and selection
  • Optimization
  • Scale-up
  • Process documentation

Chemical Research

Chem-Master International provides a one-stop, continuous range of problem-solving expertise in chemical synthesis, supported by world-class analytical services. We routinely solve complex analytical problems for our clients and offer the Chemistry Research Services either as value added or as a stand-alone service.

Services being offered include:

  • Analysis and interpretation using HPLC, GC, LC/MS, 400 Mhz NMR(1H, 13C, 19F, 31P), FT-IR.
  • Analytical methods development and validation
  • Working with complex molecules and multi-step syntheses
  • Developing and optimizing existing processes to produce a synthetic route amenable to commercial or toll manufacture
  • Chemical conversion/derivatization in support of difficult analytical determinations

Chem-Master Advantage

The Customization Advantage

Chem-Master International offers each client an excellent working relationships created by timely completion and excellent customer support of each project. Our client base consists of both large and small companies in several industry verticals such as the pharmaceutical industry, the biotechnology industry, drug discovery groups and research academic institutions.

From large scale multi-year collaboration agreements to small short-term development contracts, Chem-Master International offers each client a customized solution that best fits the customers needs.

The Project Management Advantage

With over 15 years of operating experience with a diverse range of clients, our executive team will provide ongoing project management from the start to the finish of each project. This offers our clients excellent visibility as to the progress and the milestone achievements and provides us the ability to adapt to any requested changes as well as to resolve any problems quickly and effectively.

Each project is electronically tracked along with periodic client and internal updates leading to reviews which allow for managing and charting any required metrics.

The Experienced Personnel Advantage

The Chem-Master International staff consists of scientists, laboratory technicians and support staff that have extensive experience in chemical research and development. We believe in offering and delivering quick and cost-effective results for our clients. The selective hiring, in-house training and development and high retention rates of the employees have led to a client-centric culture throughout the Company.

Our company's credo is to provide products and services of the highest quality at the most reasonable prices.

The Domestic Partner Advantage

The local presence and the established tenure of its management and the company offers our clients several advantages. From complex benefits such as Intellectual Property protection, Quality Control, Regulatory Requirements to simple benefits such as real-time interactions, On-time material procurement, product delivery times, and being local relieves our clients of the non-productive tasks and lets them concentrate on the matters of importance.

We are local and we are there when you need us

The company will undertake

  • Process and yield improvement to achieve economic or commercially acceptable levels of a desired substance
  • The development of new routes to a needed compound
  • Research to discover methods of synthesis for a new or required compound
  • The synthesis of compounds that require multi step processes (5-15 steps)
  • Consultational services both on- and off- site.