Process Chemistry

Chem-Master prides itself at being expert in assisting our clients to develop new and proprietary routes to existing compounds. We will also take an existing synthesis and develop a scalable process using our in-house talent and state-of-the-art technology, including statistical design of experiments, real-time reaction monitoring to generate detailed reaction/impurity profiles, and further process development. Our staff has experience in developing and transferring projects from our research laboratories to pilot plant scale.

One of our recent projects include is a multi-year collaboration with a biotechnology company in which the core requirement is the development of a commercial API manufacturing process starting from a multi-step medicinal chemistry route.

Services being offered include:
  • Process development
  • Route scouting and selection
  • Optimization
  • Scale-up
  • Process documentation